Physical Medicine
Targeted Exercises to Treat Your Pain

DrJEDtalks: Nerve pain Meds: Cymbalta only

Category: DrJed Talks

3min:56sec. A brief discussion of Cymbalta and dosing in the treatment of nerve pain.

WEBVTT

1
00:00:00.355 –> 00:00:02.855
In a previous video we talked about the various causes

2
00:00:03.115 –> 00:00:05.095
of neuropathic pain that is nerve pain.

3
00:00:05.485 –> 00:00:09.455
Here we’ll focus primarily on the medical treatments.

4
00:00:10.355 –> 00:00:12.775
So to review, in general, causes

5
00:00:12.775 –> 00:00:16.215
of nerve pain may be from the neural entrapments,

6
00:00:16.315 –> 00:00:19.175
the pinched nerve in the, the neck, the low back,

7
00:00:19.315 –> 00:00:22.495
or other places in the body versus the neuropathies,

8
00:00:22.585 –> 00:00:25.415
peripheral neuropathy, diabetic peripheral neuropathy.

9
00:00:25.995 –> 00:00:27.655
So what do we do about this?

10
00:00:28.045 –> 00:00:31.735
Well, the treatment of nerve pain can be very difficult.

11
00:00:32.185 –> 00:00:35.815
Nerve pain can be very resistant to standard medications

12
00:00:35.815 –> 00:00:38.295
to treat pain such as ibuprofen.

13
00:00:38.495 –> 00:00:39.895
Tylenol doesn’t really seem to do much.

14
00:00:40.005 –> 00:00:42.815
Even the narcotic pain medicines don’t treat

15
00:00:42.865 –> 00:00:43.935
nerve pain very well.

16
00:00:44.235 –> 00:00:46.495
So what are the standard treatments for nerve pain?

17
00:00:47.355 –> 00:00:50.015
The primary medical treatments for neuropathic pain

18
00:00:50.015 –> 00:00:52.295
that is nerve pain are the big three.

19
00:00:52.675 –> 00:00:56.735
So, uh, the most commonly used is gabapentin followed

20
00:00:57.395 –> 00:01:01.175
not in two distant second by Lyrica, also called pregabalin,

21
00:01:01.315 –> 00:01:02.655
and then Cymbalta.

22
00:01:02.655 –> 00:01:05.415
Those would be the big three medications that can be used

23
00:01:05.555 –> 00:01:08.815
to treat neuropathic pain, to treat nerve pain.

24
00:01:09.735 –> 00:01:12.455
Cymbalta, there’s some literature that suggests

25
00:01:12.455 –> 00:01:15.935
that Cymbalta may be the single best medication

26
00:01:16.315 –> 00:01:17.855
to treat neuropathic pain.

27
00:01:18.395 –> 00:01:21.695
So why don’t I begin with Cymbalta? Many reasons.

28
00:01:22.245 –> 00:01:24.375
Some of the main reasons might be just

29
00:01:24.685 –> 00:01:26.015
insurance stipulations.

30
00:01:26.475 –> 00:01:29.775
Myself, I’m a physiatrist. I’m not a psychiatrist.

31
00:01:30.055 –> 00:01:33.335
Psychiatrist oftentimes use Cymbalta

32
00:01:33.395 –> 00:01:35.775
to perhaps treat depression and

33
00:01:35.775 –> 00:01:38.815
or other various mood disorders.

34
00:01:39.005 –> 00:01:42.535
However, as that is not in my wheelhouse, I’m using Cymbalta

35
00:01:42.535 –> 00:01:44.135
to treat neuropathic pain.

36
00:01:44.725 –> 00:01:48.975
Typically, the guidelines that are placed there by insurance

37
00:01:49.525 –> 00:01:53.695
stipulate that I must try other medications first, try

38
00:01:53.695 –> 00:01:54.895
and fail other medications

39
00:01:54.955 –> 00:01:57.095
before they will approve Cymbalta.

40
00:01:57.755 –> 00:02:00.455
So that will oftentimes include dosing

41
00:02:00.455 –> 00:02:02.975
and trialing the gabapentin.

42
00:02:03.085 –> 00:02:04.895
Sometimes going up trying the Lyrica.

43
00:02:05.155 –> 00:02:07.135
And if a person is still having neuropathic pain,

44
00:02:07.365 –> 00:02:09.895
then progressing to the Cymbalta.

45
00:02:10.655 –> 00:02:12.415
Cymbalta dosing is a little bit different.

46
00:02:12.755 –> 00:02:16.055
It is oftentimes dosed either once daily or twice daily.

47
00:02:16.575 –> 00:02:19.135
I typically do it twice daily myself.

48
00:02:19.335 –> 00:02:21.895
’cause once again I’m trying to treat neuropathic pain

49
00:02:21.895 –> 00:02:23.015
and not a mood disorder.

50
00:02:23.405 –> 00:02:24.575
I’ll begin very low.

51
00:02:24.875 –> 00:02:28.815
Say for example, Cymbalta 20 milligrams twice a day,

52
00:02:29.545 –> 00:02:30.775
maybe do that for a month.

53
00:02:30.775 –> 00:02:33.255
You come back, we might go to 30 milligrams twice a day.

54
00:02:33.595 –> 00:02:35.655
You might go to 40 milligrams twice a day,

55
00:02:35.675 –> 00:02:36.855
up to 80 milligrams.

56
00:02:37.775 –> 00:02:39.895
Occasionally some patients will want to switch over

57
00:02:39.915 –> 00:02:41.375
to 80 milligrams once a day.

58
00:02:41.675 –> 00:02:43.815
In that case, that is acceptable in that case.

59
00:02:43.815 –> 00:02:47.015
Nothing wrong with that. And um, once you’re at 80

60
00:02:47.575 –> 00:02:51.215
milligrams, there is, uh, literature that suggests

61
00:02:51.215 –> 00:02:54.455
that increasing the dose beyond that won’t make much

62
00:02:54.455 –> 00:02:56.135
of a difference in decreasing the pain.

63
00:02:56.205 –> 00:02:58.735
However, I have a couple patients that say

64
00:02:58.735 –> 00:03:02.005
Otherwise that say that once they got to 120 milligrams,

65
00:03:02.005 –> 00:03:03.205
it made a big difference for them.

66
00:03:03.355 –> 00:03:05.805
However, in general, once you’re up

67
00:03:05.805 –> 00:03:08.005
to 80 milligrams a day on Cymbalta,

68
00:03:08.585 –> 00:03:10.845
you’re probably not gonna get much more benefit in

69
00:03:10.845 –> 00:03:12.365
decreasing that neuropathic pain.

70
00:03:13.835 –> 00:03:17.215
So that’s a quick review of the medication dosing

71
00:03:17.475 –> 00:03:20.695
and the medication use to treat neuropathic pain.

72
00:03:20.955 –> 00:03:23.135
Now there are many other specific treatments

73
00:03:23.755 –> 00:03:25.215
for neuropathic pain,

74
00:03:25.215 –> 00:03:27.215
however, those are very specific

75
00:03:27.475 –> 00:03:30.095
to very specific pathologies.

76
00:03:31.035 –> 00:03:35.215
If you have neuropathic pain, you begin with gabapentin,

77
00:03:35.435 –> 00:03:37.135
Lyrica, Cymbalta.

78
00:03:37.275 –> 00:03:40.295
If you continue to have neuropathic pain, you speak

79
00:03:40.295 –> 00:03:42.815
with your physician and see if there are other options

80
00:03:42.815 –> 00:03:44.655
that you can treat your neuropathic pain

81
00:03:44.755 –> 00:03:47.335
to help you live your life, less pain,

82
00:03:47.765 –> 00:03:49.975
improve your function, improve your mood,

83
00:03:50.005 –> 00:03:51.535
just improve your quality of life.

84
00:03:52.035 –> 00:03:53.695
So hopefully you find this helpful.

85
00:03:54.005 –> 00:03:56.335
Once again, continue to take care of yourselves and be well.